|Applciation:||For Monoclonal Antibody Production||Brand:||Dieckamnn|
Colorless C19H40 Pristane,
Monoclonal Antibody Pristane
Key words: Pristane, CAS:1921-70-6
CAS No. 1921-70-6
Molecular formula: C19H40
Appearance: colorless liquid
Packing 500ml/bottle,or packed on the clients' requirements
Documents available:COA, MSDS,NMR,GC, ISO9001, SGS
storage: Keep in RT
Pristane is an kind of immunoactivating natural product, whch is widely used as non-antigen adjuvant for monoclonal antibody production in mouse ascite, and also used as a rodent model for the study of rheumatoid arthritis by induces arthritis in rates.
Pristane is a saturated isoprenoid base on the chemical structure,have been found and isolated in the basking shark in 1948,
1, Pristane is used as protocols for antibody production.Is used to precondition the peritoneal cavity of mice, prior to the induction of ascites fluid with myeloma cells. at present, it is widely used as non-antigen adjuvant for monoclonal antibody production in mouse ascite.
Pristane is used to induce plasmacytomas in mice as models of human myltiple myeloma.It induces a disease similar to lupus erythematosus in mice, making it useful for autoimmune studies.
Pristane also induces arthritis in rats as a rodent model for the study of rheumatoid arthritis.
1, Isolation from the basking shark
2, chemical synthesis
Because, the basking shark, as a protection animal, was listed in Article II of the Washington Convention in 2002.that means, availability of pristane from natural sources by extraction from the basking shark has been limited.So, chemical synthesis is the best choice for it.
the two largest marketing are American and Japan. Because the most of manufacturers of mono-clonal antibody has been concentrated in these two country.
MAnufacturer of pristane in China
Dieckmann company is the largest manufacturer in China, which broken through the process of large scale production of pristane